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Mammalian cell colony counting > GelCount  
   
 

GelCount
A colony counter for adherent or non-adherent mammalian cell colony forming assays

       

 

Product Overview
GelCount™ is a semi-automated platform for the detection, counting and characterization of stained/adherent mammalian cell colonies or of unstained/non-adherent colonies in soft agar and other semi-solid media assays.

 
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Applications:
  Cancer Biology 
  Drug Discovery
  Soft Agar Assay  
  Tumor Cloning Assay

 

  Huge benefits in throughput and objectivity
GelCount is a cost effective and reliable solution to the problem of counting colonies manually. It not only has a dramatically effect on improving counting throughput but its inherent objectivity and consistency eliminates human error due to subjective interpretation, bias or plain fatigue - a particularly acute problem when manually counting under microscopes.

A novel imaging and sample-handling solution
Using an ingenious high depth-of-field scanning technology combined with a software-controlled sample-loading mechanism for automated handling of up to 4 multi-well plates, GelCount is capable of single-pass imaging of colonies in 3-dimensional matrices while ensuring reliable detection of colonies and spheroids down to a 30 µm diameter.

Second-generation CHARM algorithm
Using our advanced CHARM II algorithm, GelCount provides unsurpassed colony detection capabilities including resolution of overlapping colonies and differentiation of real colonies from debris, contamination and bubbles. The multi-thread aware, user-friendly software interface also provides extensive, preview-able controls for setting colony detection sensitivity, colony size thresholds and shape-related parameters.

Single, integrated platform for colony counting
GelCount represents an all-in-one solution conceived specifically to permit the user to go from colony samples to colony counts & statistics at the click of a button. Colonies are imaged, images transferred, processed & characterized and the data collated/exported from within a single, integrated hardware/software platform. Gone is the need to manually count colonies or the unsatisfactory alternative of imaging samples on one device, then transferring these to and processing them within an independent, compromised image analysis package.

Importantly, the integrated approach also permits the archiving to disk of all raw colony images, supporting full-functionality, ‘off-line’ reprocessing even where the original samples are no longer available.

Flexible and versatile, yet powerful
GelCount is suitable for counting stained or unstained colonies in semi-solid media such as soft agar, and also for counting classic stained, adherent colony types. With its easy-loading, motorized drawer system, it can process up to four multi-well plates (6-, 12-, 24-, 48- or 96-well) and up to 24 Petri dishes in a single tray for high-throughput counting.

GelCount’s feature-rich software additionally provides a wide range of statistical outputs, including means of colony diameter, colony area and ‘distance-to-nearest neighbour’. These are also available as raw 'per colony' data, providing unparalleled data extraction from every well or plate. At the touch of a button, GelCount can provide these data in the form of histograms, providing the user with hitherto unavailable information relating to colony growth dynamics.

Try GelCount for yourself
Our Sales Team will gladly discuss your requirements and assist in providing any further information you require. Live ‘webinar’ introductions can be held at any time, while on-site demonstrations may also be available, depending on your geographical location.

 

 

 

 

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